well It was about 2 months ago I had never ever ever once gotten a BLUE BOE drop in the environment... Well I had given up on the endless kills it takes to farm a mob....well I was waiting to do a run for rfk on my hunter. I started to kil some mobs outside of SM for the hearts of zeal quest...well wouldn't you know it a blue BOE axe..the blood Spiller axe...well I sold it for 90g on the AH because it would not have helped me...and with our messed up economy my auction sold in a matter of hours... even though i have never had a 50-80 This was an epic moment with my epic drop...
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My most epic drop ever was the Warden Staff in the Un'goro Crater at about level 51, just started killing random things because I only needed 1 more bar until I leveled. It was my first epic BOE loot and I've never gotten one after that one dropped. Not even in the Outlands or Northrend.
I have only played the online game a short amount of time, so it's hard to answer this question in the defined format. However, I play the TCG version of WoW and at the recent Realms Championships I won several packs and pulled an Owned Loot from one of my packs. This was epic for me because it was the first time I have EVER pulled a loot card......and on top of that I had won the pack!
Greatstaff of the Nexus was mine. This was the most epic drop I've ever got as a mage. Got it on my first run of The Eye of Eternity. I guess I got lucky.
Blinkstrike dropped for me when I first started farming the air guys on the elemental plateau. I was making a Primal Might a day at that point. I didn't even know that there were epic world drops until then. My husband's rogue was so happy that day.
This most epic loot wasnt for me per say, but for my guild. It was the final night before the release of WotlK and in the interest of nostalgia we decided to do one last BT run. It was getting late and we had just reached Illidan. We got him down after a few careless wipes, and the roar goes up as we see Warglaive of Azzinoth. It went to one of our rogues who had the main hand, and was a great way to finish TBC on a high! :D
I think my most epic loot was the Swift Brewfest Ram this year on my druid. Was happy to get that!
My most epic piece of loot was Muckbreath's Bucket, one of the mini pets you get from the daily fishing quest. What made it so amazing was that i got it within the first few days the daily fishing started and it is also extremely adorable.